ERBB2 and breast carcinoma: As for TNM stage, positive axillary lymph nodes and human epidermal growth factor receptor 2 (c-erbB2 or HER2), as traditional correlates of breast cancer prognosis, previous studies have found that patients with greater stage and the presence of axillary lymph node metastases may have more severe tumor malignancy, while neutrophils and lymphocytes are strongly associated with tumor progression (Lee, Kim & Lee, 2019); therefore, our study explains the possible reasons for the correlation of some clinicopathological features with LANR.