Dietrick et al. (30) studied 155 patients with neonatal encephalopathy, and found that the plasma level of Ng was closely related to the grading of neonatal encephalopathy, while the CSF level of Ng was related to the prognosis of neonatal encephalopathy such as cognitive, motor and language abnormalities. Here, NRGN is linked to neonatal encephalopathy.