Moderate to severe cerebral injury:Plasma Tau level: 276.7 pg/ml (13.5–554.4 pg/ml); CSF Tau level: 2,626.1 pg/ml (56.6–6,721.5 pg/ml)Cognitive abnormal or death: Plasma Tau level 284.6 pg/ml (210.8–1,410.2 pg/ml)Abnormal motor: Plasma Tau level 412.8 pg/ml (210.8–1,410.2 pg/ml)Abnormal language: Plasma Tau level 412.8 pg/ml (209.1–1,410.2 pg/ml)* In plasma, Tau level was directly associated with encephalopathy grade and MRI. Here, MAPT is linked to Encephalopathy.