Moderate to severe cerebral injury:Plasma BDNF level: 387.2 pg/ml (13.6.1–1,006.5 pg/ml); CSF BDNF level:30.3 pg/ml (30.3–30.3 pg/ml)Cognitive abnormal or death: Plasma BDNF level 9.3 pg/ml (0.5–43.8 pg/ml)Abnormal motor: Plasma BDNF level 414.6 pg/ml (77.0–868.7 pg/ml)Abnormal language: Plasma BDNF level 372.5 pg/ml (77.0–724.9 pg/ml)* In plasma, GFAP level was inversely associated with encephalopathy grade. This evidence concerns the gene GFAP and Encephalopathy.