UCHL1 and perinatal asphyxia: Using an animal model of foals with HIE, Ringger et al. (78) reported that median UCHL1 levels (6.57 ng/ml; 2.35–11.90 ng/ml) in foals with HIE were significantly higher than those of healthy controls (2.52 ng/ml; 1.4–4.01 ng/ml), the sensitivity and specificity of UCHL1 (>4.01 ng/ml) for diagnosis of HIE were respectively 70% (51%–84%) and 94% (72%–99%), and UCHL1 levels were higher in gray matter than in white matter, demonstrating that UCHL1 is a marker of brain injury in foals with HIE.