At 24 h before treatment (alone Hypothermia group): 891.56 ± 221.70 pg/ml.After hypothermia treatment:At 4th day (867.59 ± 198.99 pg/ml)At 8th day (756.58 ± 203.49 pg/ml)At 12th day (697.68 ± 168.41 pg/ml)At 8th day and At 12th day after treatment < At 24 h before treatment, p < 0.05.At 24 h before treatment (EPO + Hypothermia Group): 913.381 ± 217.46 pg/ml.After alone hypothermia treatment:At 4th day (895.73 ± 220.69 pg/ml)At 8th day (601.22 ± 187.35 pg/ml)At 12th day (517.68 ± 143.47 pg/ml)At 8th day and At 12th day after treatment < At 24 h before treatment, p < 0.05. This evidence concerns the gene EPO and Hypothermia.