An additional suggestion is to investigate patients with PRL levels greater than 100 ng/mL who use medications known to increase PRL with imaging methods.(35) Once tumor causes have been excluded, especially macroadenomas, if it is impossible to change the medication, the prescription of hormonal therapies containing estrogen associated with progestogen, should be considered in women with a uterus to minimize the consequences of hypoestrogenism. Here, PRL is linked to neoplasm.