RCC: Renal cell carcinoma, PRCC: Papillary renal cell carcinoma, FH: Fumarate hydratase, SMARCB-1: SWI/SNF‐related matrix‐associated actin‐dependent regulator of chromatin subfamily B member 1, TFE3: Transcription factor binding to IGHM enhancer 3, TFEB: Transcription factor EB, MIT: Microphthalmia, ALK: Anaplastic lymphoma kinase, ELOC: Elongin C. The gene discussed is ALK; the disease is hereditary clear cell renal cell carcinoma.