GSTM1 and cardiovascular disorder: Fluid resuscitation is needed, and a restricted red blood cell transfusion regimen should be preferred with a threshold of Hb <70 g/L with a target of 70–90 g/L after transfusion, except for patients with previous history of cardiovascular disease with a threshold of Hb <80 g/L with a target of 10.0 g/L (79), and platelets transfusion should be performed using a threshold of 50 × 109/L (82).