TRPM3 and myalgic encephalomeyelitis/chronic fatigue syndrome: Although ME/CFS etiology has been considered to be not clearly understood, post-infectious onset, dysfunction of the immune system with reduced natural killer (NK) cell cytotoxic activity, impaired calcium (Ca2+) mobilization, and the dysfunction of transient receptor potential melastatin 3 (TRPM3) ion channels are associations to ME/CFS supported by literature (29–36).