LRRC8C and cerebellar ataxia: Furthermore, the downregulation of expression levels of Ddit4, Slc38a2, Tmem267m, Lrrc8c, and setd7 genes in the brain at 4 months pi is associated with ataxia, impairment of memory, synaptic plasticity, motor, and cognitive abilities, neuronal dysfunction and degeneration, and cerebral ischemic stroke (45–48).