Furthermore, the downregulation of expression levels of Ddit4, Slc38a2, Tmem267m, Lrrc8c, and setd7 genes in the brain at 4 months pi is associated with ataxia, impairment of memory, synaptic plasticity, motor, and cognitive abilities, neuronal dysfunction and degeneration, and cerebral ischemic stroke (45–48). This evidence concerns the gene SETD7 and cerebellar ataxia.