IDH1 and brain neoplasm: Alterations in the drivers commonly affected in the other brain tumours, including IDH1/2, TP53, ATRX, TERT, EGFR and QKI, were not detected.1 Across the LGNT samples, mutual exclusivity was observed between the recurrent genomic alterations in BRAF, FGFR1, FGFR3 and PDGFRA (Fig. 3A).