In the RGNT samples, compared with the non-tumour regions, strong stainings of OLIG2, SOX10, NG2 and PDGFRA were observed in the neurocytic regions in all samples analysed, and the astrocytic regions of the same samples showed sporadic and weaker expression of OLIG2, SOX10, NG2 and PDGFRA (Fig. 5 and Supplementary Fig. 6). The gene discussed is PDGFRA; the disease is neoplasm.