In the 10 DNET and 4 MGNT samples examined, OLIG2, SOX10, NG2 and PDGFRA were concordantly expressed; compared with the normal regions, tumour regions contained markedly more cells concordantly stained with OPC markers NG2 and PDGFRA, as well as cells positively stained with the pan-oligodendrocyte lineage marker OLIG2 and SOX10 (Fig. 5, Supplementary Figs. 6–8 and Supplementary Table 3). The gene discussed is PDGFRA; the disease is neoplasm.