In addition, an increasing number of studies have identified telomerase as a promising anticancer immunotherapy target, and telomerase-based immunotherapy is a potential antitumor therapeutic strategy.1076 Antitelomerase immunotherapy exerts its antitumor effects mainly by enhancing the sensitivity of the immune system to tumor cells expressing telomerase-specific antigenic epitopes, thereby activating hTERT-specific CD8+ cells. The gene discussed is CD8A; the disease is neoplasm.