CD8A and neoplasm: In addition, we also observed a strong positive correlation of overall DEPDC5 expression with the probability of tumor infiltration by CD8+ T cells in five independently generated CRC datasets, including GSE2387832, GSE3736433, GSE1810534, GSE2151035, and GSE1753736 (Fig. 1c), indicating a strong association of DEPDC5 expression with tumor infiltration by CD8+ T cells.