No significant APOE group differences were seen in global cortical atrophy score (p = 0.52), medial temporal lobe atrophy score (p = 0.52), volumes of white matter hyperintensities (p = 0.36), entorhinal volume (p = 0.13) or parahippocampal volume (p = 0.12). This evidence concerns the gene APOE and Cerebral cortical atrophy.