INS and diabetes mellitus: The multivariable-adjusted (sex, age, APACHE II score, mechanical ventilation, creatinine, diabetes, use of glucocorticoid, and use of insulin) hazard ratios (HRs) for 30-day mortality across ascending tertiles of CGI were 1.00 (reference), 0.68 (95% CI 0.38–1.22) and 0.36 (95% CI 0.19–0.70), respectively.