PRKN and Parkinson disease: Our study included two hiPSC lines derived from healthy controls (a 71-year-old male and a 53-years old male) and two PD hiPSC lines that were derived from patients with PINK1 and PRKN mutations: a 48-year-old patient (female) with a homozygous PINK1 and heterozygous PRKN mutation and a 75-year-old patient (male) with a heterozygous PINK1 and heterozygous PRKN mutation (Supplementary Table 4 gives detailed information about mutations).