A case-control study [48] observed inflammatory markers (IL-6, IL-8, IL-17, IL-18, MIF, Hs CRP, TNF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\alpha$$\end{document}, PAI-1 and leptin) were significantly associated with OSA as compared to those without OSAs. This evidence concerns the gene IL18 and obstructive sleep apnea syndrome.