Under 660 nm near-infrared (NIR) laser irradiation, mTHPC@VeC/T-RGD NPs can kill tumor cells by inducing apoptosis and stimulating a systemic immune response, while PD-L1 blockade further suppresses tumor growth, metastasis, and forms long-term host immune memory to prevent tumor recurrence [429]. This evidence concerns the gene CD274 and neoplasm.