Regarding the constructed prognostic model (Model-ours), it consisted of seven prognostic markers, ZSCAN10, SIGLEC14, GHRHR, TBX15, TAS2R1, CDKL1, and CD101. Our model suggested that highly expressed CDKL1 and CD101 were associated with a longer TTR of GBM patients, whereas the high expression of SIGLEC14, GHRHR, TAS2R1, ZSCAN10, and TBX15 exhibited the reverse trend (Fig. 6A and Additional file 5: Fig. S2). The gene discussed is SIGLEC14; the disease is glioblastoma.