LARP6 and primary ciliary dyskinesia: An important practical implication of our work is that DNAAF6 Q171∗, a mutant of DNAAF6 found in a PCD patient, could not interact with LARP6 and not restore defects of Xenopus DNAAF6 morphants, such as morphology and motility of cilia in Xenopus epidermal MCCs.