TNF and autoimmune disease: Meanwhile, IL-10 can hinder lymphocyte infiltration in the thyroid gland and the destruction of thyroid follicular cells by inhibiting the secretions of pro-inflammatory factors and cytotoxic molecules (IL-1 and TNF-α) by IFN-γ-activated monocytes, with a certain protective effect, making IL-10 a promising candidate for an evaluation index associated with autoimmune diseases.