This result agrees with a report that also found increased MAVS gene expression in people with NASH.15 However, another study described that protein levels of MAVS were significantly downregulated in people with MASLD.16 To assess whether gene expression correlated with protein levels in our cohort samples, we used 2 different antibodies (Figure 2B, Supplemental Figures S1 and S2, http://links.lww.com/HEP/I457 and Supplemental Materials and Methods, http://links.lww.com/HEP/I457). Here, MAVS is linked to metabolic dysfunction-associated steatohepatitis.