MAPT and supranuclear palsy, progressive, 1: As the conformational and PTM state of Tau in the mouse brain does not replicate those found in human brain, we assessed the immunoreactivity of the human-specific Tau-12, SP70 and HT7, as well as that of the Tau-5, “total” Tau antibodies in FFPE brain sections from human donors diagnosed with AD, PSP and PiD (Supp.