MAPT and early-onset autosomal dominant Alzheimer disease: Another study conducted in the ADNI cohort, by Mehta et al., that included MCI and AD participants in the analysis, reported an elevated NLR to associate with greater PET measures of Aβ, but not tau, as well as with longitudinal cognitive decline determine by the Alzheimer’s Disease Assessment Scale Cognitive Subscale (ADAS-Cog) [22].