DLX5 and colorectal carcinoma: However, the role and expression of DLX5 in CRC have not yet been reported; in the present study, by conducting qPCR and western blotting assay, we found that DLX5 was upregulated in CRC cell lines (HCT116 and SW480) as compared to that in the normal colon epithelial cell line (NCM460).