We found that only CRP significantly mediated part of the relationship between depression and LTL (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$P_\text{M}=14.5\%;95\%\;\text{CI = }\lbrack3.3\%;32.1\%\rbrack$$\end{document}PM=14.5%;95%CI =[3.3%;32.1%]). The gene discussed is CRP; the disease is depressive symptom measurement.