Although FGF14 has a long-established link with ataxia, with conventional variants (point mutations, insertions and deletions) known to cause the rare SCA27A (formerly SCA27), it has been recently discovered that a STR expansion in intron 1 of FGF14 also results in an AD HCA, SCA27B [39–41]. The gene discussed is FGF14; the disease is Ataxia.