VEGFA and neoplasm: Compared to other angiogenic targets such as vascular endothelial growth factor (VEGF) and integrins, that are also involved in the general process of angiogenesis, the tumor neovascular specificity of PSMA and the potential for internalization of PSMA makes it an ideal target, reducing off-target effects, and supports development of PSMA and vascular-targeted therapies and imaging techniques for BCa [67].