During iron deficiency, IRP binding to TFRC and DMT1 3′-IREs stabilises mRNA by blocking RNase entry, promoting iron uptake, while IRP binding to 5′-IRE-containing mRNAs excludes ribosome binding and translation, suppressing iron egress and storage by ferroportin and ferritin, respectively [23]. This evidence concerns the gene WNT2 and nutritional disorder.