The latter phenotype could also be related to SWAP-70–dependent macropinocytosis and phagocytosis (Oberbanscheidt et al, 2007; Baranov et al, 2016), which require dynamic reorganization of the actin cytoskeleton and contractile activities, processes important for cancer cell invasion (Montcourrier et al, 1994). This evidence concerns the gene SWAP70 and cancer.