Although a few studies have identified differentially expressed ferroptosis-related genes in gastric cancer, such as tumor necrosis factor (TNF), dual specificity phosphatase 1 (DUSP1), and mitochondrial lon peptidase 1 (LONP1),[13–15] ferroptosis-related genes involved in therapy resistance in gastric cancer and their associations with the prognosis of patients remain unclear. The gene discussed is DUSP1; the disease is gastric cancer.