ESR1 and meningioma: Hua, et al. [54] reported the high expression of ER was independently associated with poor prognostic outcomes of OS and PFS of the WHO grade III meningioma patients by multivariate Cox regression analysis (HR = 1.958, 95% CI 1.364–2.809 and HR = 1.515, 95%CI 1.115 to 2.058).