NF1 and melanoma: Two of three (67%) NF1-mutant melanomas with missense (putatively activating) mutations in NF1 harbored chromothripsis, compared with 6 of 16 (37.5%) NF1-mutant melanomas with putatively inactivating mutations in NF1, although this difference was not statistically significant (Fisher’s exact test, P > 0.05).