In the multivariate analysis, HMGA1 [HR = 1.77 (95% CI 1.19–2.61), p = 0.004], HMGB1 [HR = 1.59 (95% CI 1.07–2.37), p = 0.023] and HMGB2 [HR = 1.74 (95% CI 1.19–2.57), p = 0.005] gene expression and diagnosis of L-sarcoma [HR = 0.61 (95% CI 0.41–0.89), p = 0.010] were the only variables independently associated with PFS (Supplementary Table S4). The gene discussed is HMGB1; the disease is sarcoma.