In addition to the direct therapeutic effects of drugs as targets, mucin can also be used to prepare vaccine-assisted therapy.Muc16-related vaccines are primarily anti-human CA-125 recombinant antibodies (Abagovomab (ACA125)), which can induce an immune response against ovarian cancer, but with modest efficacy [91] (ClinicalTrials.gov identifier:NCT00418574). Here, MUC16 is linked to ovarian carcinoma.