Cadherin 8: cadherins facilitate vascular smooth muscle cell–ECM interaction.38Tenascin: ECM protein. Bone sialoprotein 2: complexes with hydroxyapatite, forms the mineralized matrix. Periostin: facilitates cell–matrix crosstalk, contributes to myocardial fibrosis.31Sushi, von Willebrand factor type A: cell attachment process. This evidence concerns the gene PROS1 and Myocardial fibrosis.