MMP2 and neoplasm: According to current studies, CAFs could produce various pro‐tumor factors, such as matrix metalloproteinases (Mmp) 2 (Mmp2), and Il‐6 to enhance tumor migration, invasion, and drug‐resistance and to generate an immune‐suppressive TME.[34, 35] We examined expression levels of these genes in CAFs after different treatments and observed a widely expression inhibition of these pro‐tumor factors (Figure S10a, Supporting Information).