EGFR and breast cancer: To this regard, we note that, while we report that some of the PETsign genes (CXCL8 and EGFR) might be involved in determining metabolic cell‐autonomous effects in BC, the role of non‐cell‐autonomous circuitries, involving tumor:stroma interactions and the establishment of hypoxic conditions, which play key roles in determining the glycolytic phenotype of tumors, was not addressed in our study, and remains therefore to be elucidated.