According to dbEMT-2.0, in our 88 KDM7A-DT down-regulating EMT Type II pathway–associated gene signature, only PDGFRB is associated with oncogenic role, WNT5A is related to dual (tumor suppressor- and oncogenic- like) functions, and seven genes (IGFBP3, CDH11, ITGA5, LOX, CD44, ITGB1, and FBLN1) are EMT pathway–associated tumor suppressor genes. The gene discussed is IGFBP3; the disease is neoplasm.