Multiple important risk factors include increased age, nursing home residency, previous hospital admission within 30 days, higher environmental temperature, serum creatinine, bilirubin, C-reactive protein, white blood cell, alanine aminotransferase (ALT), and lower serum sodium and albumin; diabetes, urological obstruction, sepsis, and gastrointestinal medical condition, higher pre-admission mean creatinine, lower baseline eGFR, chronic kidney disease, prior history of AKI, lung disease, hyperlipidaemia, infections, antibiotics use. The gene discussed is GPT; the disease is infection.