(chai hu) exerted anti-inflammatory and neuroprotective effects as they can alleviate mitochondria damage in MPTP-induced PD mouse models (Jeong et al., 2018), regulate nuclear receptor-related 1 protein (Sim et al., 2017), and suppress NF-κb-mediated inflammatory pathways (Park et al., 2015). This evidence concerns the gene NFKB1 and Parkinson disease.