IL-17A and IL-18 levels have been shown to be elevated in the serum and gingival crevicular fluid of periodontitis patients as well as being correlated with periodontal disease clinical manifestations severity (Borilova Linhartova et al., 2016; Techatanawat et al., 2020; Zhong, 2014). Here, IL17A is linked to periodontal disorder.