The study conducted in America and Europe revealed that different populations possess similar genes, namely ABCA7, ARID5, CD33, CD2AP, EPHA1, and MS4A, with polymorphism rs3764650, rs2588969, rs3865444, rs9349407, rs11767557, and rs610932, rs670139 respectively, responsible for causing AD in specific regions. The gene discussed is EPHA1; the disease is Alzheimer disease.