CRP and abscess: Defined as an AL requiring active therapeutic intervention (administration of antibiotics, interventional drainage, or transanal drainage). Such leaks are usually managed without operative reintervention. Clinical symptoms associated with Grade B leaks include mild/moderate discomfort with abdominal/pelvic pain, leukocytosis, elevated serum C-reactive protein (CRP), and turbid/purulent rectal or vaginal discharge. Radiological evaluation conducted on these patients show leakage of the endoluminally administered contrast agent at the anastomosis. CT scans may also reveal abscess formation.