MAPT and early-onset autosomal dominant Alzheimer disease: We have utilized the following keywords: "Alzheimer's disease," OR “Alzheimer's disease pharmacotherapy,” OR “Novel Alzheimer’s treatments,” OR “monoclonal antibodies for Alzheimer’s disease,” OR “Alzheimer’s treatments targeting Tau,” OR “Alzheimer’s Anti-inflammatory drugs,” OR “Alzheimer’s supplements.” The search was limited to phase three clinical trials and meta-analyses published in peer-reviewed journals for medications currently available.