Moreover, D-dimer levels decreased after short-time systemic prednisolone administration, accompanied by remission of clinical symptoms and decrease of peripheral eosinophil counts and IgE levels.<h4>Conclusion</h4>Elevation of D-dimer in EGID may not represent thrombotic events but is possibly associated with disease severity. The gene discussed is IGHE; the disease is eosinophilic gastrointestinal disease.