IGHE and cystic fibrosis: A meta-analysis [479], which summarized the results of the use of recombinant Asp f allergens in 26 studies (with a total of 1,694 patients), showed that IgE against Asp f 1 or Asp f 3 has the highest sensitivity (96.7% in asthmatics and 93.3% in CF patients) to differentiate ABPA patients from these patients, but Asp f 4 or Asp f 6 had the highest specificity with 99% in asthmatics versus Asp f 6 alone with 98% in people with CF.