ALMS1 and cardiomyopathy: We did not find evidence of cardiomyopathy in Alms1 KO mice at P15, which is at odds both with the previous demonstration of increased heart/body mass ratio and persistent cardiomyocyte mitosis in Alms1GT/GT mice, and with mitogenic cardiomyopathy in four infants carrying biallelic ALMS1 mutations (Shenje et al., 2014).