The following genes were reported to be differentially methylated in T2DM compared to normoglycemic controls in independent candidate-gene DNA methylation studies in the same tissue as the initial discovery group—ABCG1 [62, 63], FTO [64–66], TXNIP [67] and KCNQ1 [64, 68] in PBMCs, and PPARGC1A in pancreatic islets [69]. Here, PPARGC1A is linked to type 2 diabetes mellitus.