Considering the high antioxidant potential of GSE and the role of inflammation and oxidative stress in NAFLD, GSE affects the severity of hepatic steatosis by reducing inflammatory factors such as hs-CRP, TNF-α, and oxidative stress (MDA), as well as increasing antioxidant enzymes (SOD and CAT) [55, 56]. Here, SOD1 is linked to Hepatic steatosis.