Considering the high antioxidant potential of GSE and the role of inflammation and oxidative stress in NAFLD, GSE affects the severity of hepatic steatosis by reducing inflammatory factors such as hs-CRP, TNF-α, and oxidative stress (MDA), as well as increasing antioxidant enzymes (SOD and CAT) [55, 56]. The gene discussed is CAT; the disease is metabolic dysfunction-associated steatotic liver disease.