SLC39A4 and acrodermatitis enteropathica: The genetic disease, known as acrodermatitis enteropathica (AE, OMIM #201,100), is a rare autosomal recessive disease due to a mutation of the SLC39A4 gene (MIM #607,059), which encodes zinc/iron-regulated transporter-like protein 4 (ZIP4), leading to an impaired zinc absorption from the intestine [4, 5].