Log likelihood ratio test results comparing linear regression model with two piece wise linear regression model adjusted for gender, age, race/ethnicity, PIR, educational status, marital status, BMI, HbA1c, serum total cholesterol, diabetes medication use, diabetes duration, Insulin therapy, Serum cotinine, calcium, serum triglycerides, urine albumin, magnesium, vitamin D, alcohol intake, multivitamin supplements use, kidney disease, TEI, HEI, HOMA-IR, hypertension, hyperlipidemia, CVD, smoke, physical activity. The gene discussed is INS; the disease is hyperlipidemia.