Methylation markers considered suitable for the detection of ovarian cancer include a combination of markers described in studies on cervical and endometrial cancer detection in patient-friendly sample types (GALR1, GHSR, MAL, PRDM14, SST, and ZIC110,23–25), and ovarian cancer detection in cervical scrapes and plasma (C2CD4D, CDO1, NRN117,26–28). The gene discussed is CDO1; the disease is ovarian cancer.